Status:

RECRUITING

A Multimodal Approach for Clinical Diagnosis and Treatment of Primary Progressive Aphasia, MAINSTREAM ID:3430931

Lead Sponsor:

IRCCS Centro San Giovanni di Dio Fatebenefratelli

Collaborating Sponsors:

Fondazione Regionale per la Ricerca Biomedica

Fondazione Mondino

Conditions:

Primary Progressive Aphasia

Eligibility:

All Genders

40+ years

Phase:

NA

Brief Summary

Primary Progressive Aphasia (PPA) is a syndrome due to different neurodegenerative disorders selectively disrupting language functions. PPA specialist care is underdeveloped. There are very few specia...

Detailed Description

60 patients with PPA will be recruited from IRCCS Istituto Centro San Giovanni di Dio, Fatebenefratelli, Brescia; IRCCS Fondazione Istituto Neurologico Nazionale C. Mondino, Pavia; Fondazione IRCCS Ca...

Eligibility Criteria

Inclusion Criteria:

  • Diagnosis PPA according to the current clinical criteria (Gorno-Tempini et al., 2011);
  • Mild PPA defined using the Progressive Aphasia Severity Scale (PASS);
  • Italian native speakers.

Exclusion Criteria:

  • Presence of developmental disorders;
  • Presence of any medical or psychiatric illness that could interfere in completing assessments;
  • Presence of any medical condition that represents a contraindication to tDCS.

Key Trial Info

Start Date :

February 1 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

February 1 2026

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT05730023

Start Date

February 1 2023

End Date

February 1 2026

Last Update

September 19 2024

Active Locations (4)

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Page 1 of 1 (4 locations)

1

Maria Cotelli

Brescia, BS, Italy, 25125

2

Tiziana Carandini

Milan, MI, Italy, 20122

3

Francesca Baglio

Milan, MI, Italy, 20148

4

Stefano F. Cappa

Pavia, PV, Italy, 27100