Status:

RECRUITING

Global PNH Patient Registry

Lead Sponsor:

Aplastic Anemia and MDS International Foundation

Collaborating Sponsors:

National Organization for Rare Disorders

Conditions:

Paroxysmal Nocturnal Hemoglobinuria

Eligibility:

All Genders

Brief Summary

The primary aim of the Global Paroxysmal Nocturnal Hemoglobinuria (PNH) Patient Registry is to conduct a prospectively-planned and efficient natural history study that will result in a more comprehens...

Detailed Description

The Global PNH Patient Registry is a prospective, longitudinal, web-based, observational natural history study. Participants with PNH will be followed throughout the course of their lives with either ...

Eligibility Criteria

Inclusion Criteria:

- Individuals of any age with a confirmed diagnosis of PNH or diagnosis consistent with PNH are eligible for inclusion. PNH is defined as a genetic mutation in the PIG-A gene.

Individuals must be willing to provide informed consent. Participants can be:

  • legal adult participants who are able to provide their own consent;
  • children and adults unable to provide their own consent, for whom consent must be provided by a Legally Authorized Representative (LAR) who is a legal adult.
  • Individuals must have at least periodic access to the internet and be able to comply with web-based study procedures and data collections

Exclusion Criteria:

  • Individuals not able to read and understand English.

Key Trial Info

Start Date :

May 6 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

May 6 2031

Estimated Enrollment :

500 Patients enrolled

Trial Details

Trial ID

NCT05755867

Start Date

May 6 2021

End Date

May 6 2031

Last Update

February 20 2025

Active Locations (1)

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Aplastic Anemia and MDS International Foundation

Bethesda, Maryland, United States, 20814