Status:

RECRUITING

High- Versus Low-calcium Water for Bone Health

Lead Sponsor:

I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio

Conditions:

Orthopedic Disorder

Calcium Metabolism Disorders

Eligibility:

All Genders

25-55 years

Phase:

NA

Brief Summary

The experimental study investigates which metabolic responses of calcium and parathyroid hormone are observable in blood and urine in a cohort of 41 healthy adults following a sequence of different ex...

Eligibility Criteria

Inclusion Criteria:

  • Body mass index ≥ 18 and < 30
  • Maintenance of diet and physical activity lifestyle throughout the duration of the study
  • Acceptance of informed consent

Exclusion Criteria:

  • Consumption of water with calcium > 150 mg/L
  • Pregnancy (as established by self-declaration), breastfeeding, menopause
  • Inability to follow the study protocol
  • Cardiac, vascular, renal, and oncological disease
  • Neuropsychiatric disease, developmental disorders
  • Disease or past surgery affecting the gastrointestinal tract
  • Drugs that interfere with bone (e.g. corticosteroids) or with fluid balance (e.g. diuretics)

Key Trial Info

Start Date :

March 2 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 31 2026

Estimated Enrollment :

41 Patients enrolled

Trial Details

Trial ID

NCT05772364

Start Date

March 2 2023

End Date

May 31 2026

Last Update

May 6 2023

Active Locations (1)

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1

IRCCS Istituto Ortopedico Galeazzi

Milan, Italy