Status:

RECRUITING

A Novel Integrative Non-invasive Embryo Selection Approach for IVF Based on MK-RS Analysis

Lead Sponsor:

Chinese University of Hong Kong

Conditions:

Reproductive Issues

Subfertility

Eligibility:

All Genders

Phase:

NA

Brief Summary

During assisted reproductive technology treatment, embryo selection is an important process that may affect the clinical pregnancy rate. Many assisted reproductive technology units over the world have...

Detailed Description

Our study will include two phases. In Phase I (a retrospective study), archived data will be collected to train the CNN-enhanced MK with RS method on embryo selection, leading to the integrated approa...

Eligibility Criteria

Inclusion Criteria:

  1. Patients undergoing IVF/ ICSI treatment
  2. Patients receiving the first, second or third IVF/ICSI treatment cycle
  3. Patients and their partners willing to sign the informed consent agreement
  4. Patients having at least three normal fertilised embryos on the day of the fertilization check
  5. Consecutive women undergoing IVF treatment
  6. Patients planning to use a time-lapse incubator for embryo culture

Exclusion Criteria:

  1. Day one human embryos with blur imaging
  2. Large obstructions in the embryo area
  3. More than half of the embryo area is blocked by the well or degeneration
  4. Patients with more than half of the embryos without sufficient spent culture medium for RS analysis
  5. Patients with known genetic diseases

Key Trial Info

Start Date :

July 17 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2026

Estimated Enrollment :

176 Patients enrolled

Trial Details

Trial ID

NCT05896709

Start Date

July 17 2023

End Date

December 1 2026

Last Update

March 21 2025

Active Locations (1)

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1

The Chinese University of Hong Kong

Hong Kong, Hong Kong