Inclusion Criteria Mother:

• Willing and able to provide signed and dated informed consent form
• 18 years of age or older
• Documented HIV seropositive
• Antiretroviral therapy initiated before the third trimester of pregnancy
• Planning on exclusively breastfeeding the infant for the first 6 months of life

Inclusion Criteria Infant:

• Documented HIV seronegative at birth
• Born at term (completed at least 37 weeks of gestation)
• Birth weight >2.4kgs

Exclusion Criteria:

• Severe illnesses, e.g. Sepsis
• current TB or known household TB contact
• Chronic disorder or medications (other than antiretrovirals and cotrimoxazole prophylaxis) that in the opinion of the investigator would alter immunity
• Pregnancy or delivery complications including birth asphyxia, seizures, sepsis, major congenital anomalies or congenital infections
• Known contraindications to components of the interventional products
• Taking additional probiotics or prebiotics
• Any condition that in the opinion of the investigator would make participation in the trial unsafe