Status:
UNKNOWN
Use of Dual-light Photodynamic Therapy as an Adjunct to Periodontal Treatment in Smokers
Lead Sponsor:
Aristotle University Of Thessaloniki
Collaborating Sponsors:
University of Helsinki
Conditions:
Periodontitis
Dual- Light Photodynamic Therapy
Eligibility:
All Genders
35+ years
Phase:
NA
Brief Summary
The goal of this controlled clinical trial is to investigate the impact of regular home use of Lumoral device as an adjunct treatment compared to non-surgical periodontitis treatment (NSPT) alone on b...
Detailed Description
The objective of this study is to investigate the impact of regular home use of Lumoral device® as an adjunct treatment compared to non-surgical periodontal treatment alone on biofilm removal and host...
Eligibility Criteria
Inclusion
- Periodontal disease Stage III and Grade C with at least 6 sites with probing depth (PD) and clinical attachment loss (CAL) ≥5 mm and bleeding on probing (BoP) ≥15 teeth
- aged ≥35
- Smokers smoking ≥10 cigarettes per day
Exclusion
- Patients allergic to indocyanine
- Patients with active carious lesions
- Need for prophylactic antimicrobial coverage
- Scaling and root planing in the previous 6 months
- Non-smoking status or smoking less than 10 cigarettes per day
- Antimicrobial therapy in the previous 6 months
- Immunomodifying conditions/ diseases (e.g. diabetes mellitus, rheumatoid arthritis, osteoporosis)
- Long-term use of medication that could interfere with periodontal response (e.g. biphosphonates)
- Pregnancy or lactation
Key Trial Info
Start Date :
January 23 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2024
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT05962801
Start Date
January 23 2023
End Date
September 1 2024
Last Update
October 4 2023
Active Locations (1)
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1
Dental School of Aristotle University of Thessaloniki
Thessaloniki, Greece, 54124