Status:
RECRUITING
Brain, Psychological and Epigenetic Determinants for Optimizing the Treatment of Chronic Low Back Pain
Lead Sponsor:
Université de Sherbrooke
Conditions:
Chronic Low-back Pain
Eligibility:
All Genders
18-75 years
Brief Summary
The goal of this observational study is to better understand the role of the brain in chronic low back pain patients.
Detailed Description
Chronic pain affects millions of people worldwide, and the main cardinal sign of any arthritis condition is pain. Several arthritis conditions can cause chronic low back pain (CLBP).The mechanisms tha...
Eligibility Criteria
Inclusion
- Low back pain (≥ 6 months) with or without pain radiating to the legs or radiating to the neck
- Positive medial branch blocks, suggesting that the pain originates from the lumbar facet joints
- Average pain intensity of ≥ 3/10 in the 24-hour period before the initial visit
- Pain primarily localized in the lower back
Exclusion
- Inadequate pain relief or relief of less than three months following selective thermoablation of medial lumbar branches by radiofrequency
- Neurological, cardiovascular, or pulmonary disorders
- Comorbid pain syndrome
- History of surgical intervention in the back
- A corticosteroid infiltration within the past year
- Pregnancy (current or planned during the course of the study)
- Contra-indication to Magnetic Resonance Imaging (MRI)
Key Trial Info
Start Date :
September 7 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 16 2027
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT05963451
Start Date
September 7 2023
End Date
July 16 2027
Last Update
September 13 2023
Active Locations (1)
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1
Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke (CRCHUS)
Sherbrooke, Quebec, Canada, J1H 5N4