Status:
UNKNOWN
Effect of Peripapillary Atrophy to Diagnose Glaucoma in High Myopia
Lead Sponsor:
Zhongshan Ophthalmic Center, Sun Yat-sen University
Conditions:
Myopia
Refractive Errors
Eligibility:
All Genders
18+ years
Brief Summary
This study intends to analyze the characteristics between peripapillary retinal nerve fiber layer thickness and peripapillary area in high myopia with or without glaucoma
Detailed Description
Glaucoma is the leading cause of irreversible blindness in the world. Myopia is a risk factor for glaucoma. With the rising prevalence of both myopia and glaucoma in an ageing population, the occurren...
Eligibility Criteria
Inclusion
- Age ≥18 years.
- Equivalent spherical ≤-6D or axial length ≥26.5mm.
- High myopia with primary open angle glaucoma, such as anterior chamber angle is opening, optic rim defect, RNFL loss, etc.
- The peripapillary region can be accurately defined Based on OCT.
Exclusion
- (1) Exclusion criteria for high myopia group:
- History of glaucoma and elevated intraocular pressure.
- History of uveitis or intraocular surgery.
- History of other retinal optic nerve or related systemic diseases.
- The examination results are unreliable, such as poor image quality.
- (2) Exclusion criteria for high myopia with primary open angle glaucoma group:
- Others nervous system diseases, such as visual field loss or optic nerve damage.
- Others non-glaucomatous ocular pathologies may affect the visual field or retinal nerve fiber layer status, such as retinal diseases, uveitis, or ocular surgery history.
Key Trial Info
Start Date :
August 1 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 31 2025
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT05964634
Start Date
August 1 2023
End Date
January 31 2025
Last Update
July 28 2023
Active Locations (1)
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1
Zhongshan Ophthalmic Center, Sun Yat-sen University
Guangzhou, Guangdong, China, 510060