Status:
RECRUITING
Exercise Training Influences Gut Microbiota and Cardiovascular Health Through Inflammation Control in Adult Hypertensive Population: the MicroFit Study
Lead Sponsor:
University of Bologna
Collaborating Sponsors:
Actial Farmaceutica S.r.l.
Conditions:
Hypertension
Microbiota
Eligibility:
All Genders
40-65 years
Phase:
NA
Brief Summary
Cardiovascular diseases are the number 1 cause of death globally, taking an estimated 17.9 million lives each year (31% of deaths worldwide). Hypertension, with 1.13 billion people affected worldwide,...
Eligibility Criteria
Inclusion
- Arterial hypertension\*;
- Stable antihypertensive therapy in the last 2 months, with controlled blood pressure values;
- Age 40-65 years;
- Willing to sign the written informed consent;
- Written and spoken Italian language comprehension.
Exclusion
- Atrial fibrillation;
- Diabetes mellitus either type I or II;
- Active cancer;
- Inflammatory bowel disease;
- Heart failure NYHA class III to IV;
- Recent antibiotic or probiotic treatment in the previous month for any reason;
- Recent myocardial infarction or hospital admission for any other reason in the previous 6 months;
- Any other condition that the medical doctor (MD) considers to contraindicate the participation in an exercise program of High intensity;
- Pulmonary disease requiring oxygen therapy;
- Relevant neurological condition impairing motor or cognitive function;
- Severe depressive disorder;
- Pregnancy.
Key Trial Info
Start Date :
April 3 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 2 2026
Estimated Enrollment :
75 Patients enrolled
Trial Details
Trial ID
NCT05967715
Start Date
April 3 2023
End Date
April 2 2026
Last Update
August 1 2023
Active Locations (1)
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1
University of Bologna
Bologna, Italy, 40138