Status:
RECRUITING
Evaluation the Efficacy Between Botox Injection and Combination Pharmacotherapy in Patients With Detrusor Overactivity
Lead Sponsor:
Mackay Memorial Hospital
Conditions:
Urinary Bladder, Overactive
Urodynamics
Eligibility:
FEMALE
20-90 years
Phase:
PHASE4
Brief Summary
To investigates the effects of botulinum toxin type A bladder injection compared to combined pharmacotherapy with Mirabegron and Solifenacin.
Detailed Description
Patients with detrusor overactivity who were refractory to monotherapy with either anti-muscarinics or β3-adrenoceptor agonists were enrolled for prospective study. Patient were divided in two groups,...
Eligibility Criteria
Inclusion
- Patients with detrusor overactivity which defined as a urodynamic observation characterized by involuntary detrusor contractions during the filling phase. Those who were refractory to monotherapy with either anti-muscarinics or β3-adrenoceptor agonists were enrolled for prospective study
Exclusion
- Postvoid urine retention before treatment
Key Trial Info
Start Date :
October 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2026
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT05968885
Start Date
October 1 2021
End Date
December 31 2026
Last Update
May 9 2025
Active Locations (1)
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1
Mackay Memorial Hospital
Taipei, Taiwan