Status:

COMPLETED

Cysteamine Compared to Hydroquinone in Melasma

Lead Sponsor:

China Medical University Hospital

Conditions:

Melasma

Eligibility:

All Genders

20+ years

Phase:

PHASE3

Brief Summary

Melasma is an acquired pigmentary disorder of symmetrical hyperpigmentation appearing as variable darkness macules and patches over the forehead, cheeks, and chin, even sun-exposed areas of the body. ...

Eligibility Criteria

Inclusion

  • a history of epidermal type melasma as diagnosed by a board-certified dermatologist
  • above the age of 20 years
  • Fitzpatrick skin type II-V

Exclusion

  • pregnant
  • breastfeeding
  • currently receiving oral contraceptive pill or hormonal therapy
  • have received topical hydroquinone, retinoid, tranexamic acid, or steroid treatment within the past month
  • have received laser therapy or any other phototherapy within the past three months
  • a history of allergic reactions to hydroquinone or cysteamine
  • other pigmentary disorders of the face
  • systemic diseases that may affect pigmentation of the face (such as systemic lupus erythematosus, jaundice, end-stage renal disease)

Key Trial Info

Start Date :

November 28 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 11 2020

Estimated Enrollment :

28 Patients enrolled

Trial Details

Trial ID

NCT05969587

Start Date

November 28 2019

End Date

November 11 2020

Last Update

August 7 2023

Active Locations (1)

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China Medical University Hospital

Taichung, Taiwan, 404332