Status:
ACTIVE_NOT_RECRUITING
Radiomics-Based Visualization and Quantitative Validation of IDH1 Heterogeneity in Gliomas
Lead Sponsor:
Mingge LLC
Collaborating Sponsors:
Huashan Hospital
Fudan University
Conditions:
Glioma, Malignant
Computer-Assisted
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
The goal of this clinical trail is to non-invasively visualise and quantitatively validate an radiomics model of genetic heterogeneity in adult patients with diffuse glioma to help clinicians better g...
Detailed Description
BACKGROUND The WHO 2016 officially introduced molecular markers into the pathological diagnosis of gliomas, marking a step into the era of molecular diagnosis of gliomas. Among them, isocitrate dehyd...
Eligibility Criteria
Inclusion
- Patients aged 18-70 years, male or female;
- Patients with complete preoperative magnetic resonance imaging and were initially diagnosed with glioma based on the magnetic resonance imaging results;
- Patients who were proposed for craniectomy without contraindications to surgery and who had signed an informed consent form by themselves or their proxy;
- Patients with confirmed diagnosis of glioma by postoperative pathological diagnosis.
Exclusion
- Patients to be admitted for a simple puncture biopsy;
- Patients with a combination of serious medical conditions and those who cannot tolerate surgery;
- Patients with a bleeding tendency or abnormal coagulation function, or those who have not discontinued long-term use of anticoagulants such as aspirin and clopidogrel;
- Pregnant and breastfeeding women;
- Patients participate in other clinical trials during the same period.
Key Trial Info
Start Date :
March 15 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 15 2026
Estimated Enrollment :
18 Patients enrolled
Trial Details
Trial ID
NCT05969691
Start Date
March 15 2019
End Date
December 15 2026
Last Update
August 8 2023
Active Locations (1)
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1
Huashan Hospital, Fudan University
Shanghai, Shanghai Municipality, China, 200433