Status:
RECRUITING
Comparison of Live Birth Rate in Natural Cycle Single Euploid FET Versus Without Luteal Phase Support
Lead Sponsor:
ART Fertility Clinics LLC
Conditions:
Pregnancy Related
Infertility, Female
Eligibility:
FEMALE
18-40 years
Phase:
PHASE1
Brief Summary
To evaluate whether single euploid embryo transfer in NC without routinely administered LPS is non-inferior to NC with routinely administered LPS.
Detailed Description
In case the study will show that the live birth rate in single euploid NC frozen embryo transfer cycles without LPS is not inferior to NC cycles with LPS, treatment can be simplified, and participants...
Eligibility Criteria
Inclusion
- Age: 18 to 40 years
- Regular ovulatory cycles
- Availability of at least one euploid embryo after Trophectoderm biopsy for PGT-A on day 5 or day 6
- Detection of ovulation by P4 rise \> 1.0 ng/ml after LH surge
- P4 value of at least 5 ng/ml on day 4 after ovulation
Exclusion
- History of repeated pre-menstrual spotting
- Factors affecting the implantation through anatomical changes of the uterus / ovaries or the tubes (adenomyosis, Asherman syndrome, endometriosis, uterine fibroids / polyps, isthmocele with intracavitary fluid presence, hydrosalpinx….)
Key Trial Info
Start Date :
September 5 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 30 2026
Estimated Enrollment :
342 Patients enrolled
Trial Details
Trial ID
NCT05969795
Start Date
September 5 2023
End Date
September 30 2026
Last Update
January 9 2025
Active Locations (3)
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1
ART Fertility Clinics LLC
Abu Dhabi, United Arab Emirates, 60202
2
ART Fertility Clinics Al Ain
Al Ain City, United Arab Emirates
3
ART Fertility Clinics Dubai
Dubai, United Arab Emirates