Status:
NOT_YET_RECRUITING
Clonal Hematopoiesis of Immunological Significance
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Collaborating Sponsors:
Sorbonne University
Institut National de la Santé Et de la Recherche Médicale, France
Conditions:
Immune System Diseases
Autoimmune Diseases
Eligibility:
All Genders
18+ years
Brief Summary
Ambispective, national, multicenter observational cohort study aimed at characterizing the satellite dysimmune manifestations of clonal hematopoiesis, including Vexas (Vacuoles, E1 enzyme, X-linked, A...
Detailed Description
The clinical spectrum of dysimmune manifestations associated with blood diseases is wide. The pathophysiology of these manifestations is not well understood and their management is poorly codified. Th...
Eligibility Criteria
Inclusion
- Age \>=18 years old
- Confirmed dysimmune manifestations: clinical or biological abnormality or systemic disease
- Presence or absence of myeloid or lymphoid blood disease according to World Health Organization (WHO) classification
Exclusion
- Persons benefiting from special protection: adults under guardianship and curatorship; people hospitalized without their consent and not protected by law; persons deprived of liberty.
- Persons not affiliated to the social security system
Key Trial Info
Start Date :
September 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
September 1 2045
Estimated Enrollment :
1000 Patients enrolled
Trial Details
Trial ID
NCT05969821
Start Date
September 1 2025
End Date
September 1 2045
Last Update
June 12 2025
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