Status:

RECRUITING

Can Second Resection for pT1 Bladder Cancer be Avoided After Initial En-Bloc Resection With Negative Safety Margins

Lead Sponsor:

Mansoura University

Conditions:

Bladder Cancer Stage I

Eligibility:

All Genders

18-80 years

Brief Summary

The goal of this \[ Can second resection for pT1 bladder carcinoma be safely avoided after initial En-Bloc Resection with negative vertical and horizontal safety margins ? is to assess the impact of a...

Detailed Description

Bladder cancer (BC) is the one of the most prevalent cancer in Egypt representing nearly 30% of all cancers. Approximately 75% of newly diagnosed BC present with non-muscle invasive disease (NMIBC). I...

Eligibility Criteria

Inclusion

  • • Patients treated with ERBT and diagnosed with pT1 disease with negative vertical and horizontal safety margins at final pathology.

Exclusion

  • Large tumors not suitable for ERBT
  • Residual tumor.
  • Multicentric tumors ( more than 4 lesions)
  • Presence of CIS.
  • Positive vertical or horizontal safety margins after initial resection.

Key Trial Info

Start Date :

July 1 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2025

Estimated Enrollment :

370 Patients enrolled

Trial Details

Trial ID

NCT05969964

Start Date

July 1 2023

End Date

December 1 2025

Last Update

October 30 2024

Active Locations (1)

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Urology and nephrology center, Mansoura University

Al Mansurah, Dakahlia Governorate, Egypt, 35516