Status:
UNKNOWN
Cervical Epidural and Stellate Ganglion Block in Upper Limb Complex Regional Pain Syndrome
Lead Sponsor:
Tanta University
Conditions:
Stellate Ganglion Block
Cervical Epidural
Eligibility:
All Genders
21+ years
Phase:
PHASE4
Brief Summary
Evaluate the efficacy of two regimens of management in relieving chronic refractory pain in patients with upper limb complex regional pain syndrome after orthopedic trauma
Detailed Description
Ideal therapy for Complex Regional Pain Syndrome is multimodal with the use of physical therapy, psychotherapy, and pharmacologic therapy to complement interventional procedures. Within pharmacotherap...
Eligibility Criteria
Inclusion
- Patients aged more than 21 years old of both sexes with American Society of Anesthesiologists I and II
- Upper limb trauma patients with pain disproportionate to the degree of tissue injury and persists beyond the normal expected time for tissue healing
- Patients diagnosed as (Complex Regional Pain Syndrome ) based on Budapest criteria There should be at least one symptom or sign in three of the four previous categories that can not be explained by other diagnosis.
- The average daily pain intensity required on Numerical Rating Scale is 7 or more for at least 3 months despite of standard therapy which includes: (pharmacologic therapy Non-steroidal anti-inflammatory drugs, Antiepileptic drugs(AEDs), antidepressants), as well as physical therapy and psychiatric care.
Exclusion
- Patient refusal
- Patients with unstable psychological or psychiatric conditions, including: untreated bipolar disorder, post-traumatic stress disorder, major depression, severe personality disorder and psychotic illness
- Patients have recently undergone major interventional pain procedures, such as nerve blocks or implantable therapies.
- Patients with known drug dependency or substance use disorder specifically related to ketamine or other psycho-stimulant drugs
- Patients with previous severe reactions, contraindication or allergy to ketamine
- Patients with hepatic or renal impairment
- Active infection at the injection site
- Known allergies to medications
- Previous neck surgeries
- Raynaud's disease or Raynaud's phenomena
- Coagulopathy
Key Trial Info
Start Date :
August 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2024
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT05970146
Start Date
August 1 2023
End Date
June 1 2024
Last Update
September 5 2023
Active Locations (1)
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1
Tanta University
Tanta, El-Gharbia, Egypt