Status:
RECRUITING
Effect of RIC on Cerebral Autoregulation in Patients Undergoing Cerebrovascular Stent Implantation
Lead Sponsor:
Yi Yang
Conditions:
Remote Ischemic Conditioning
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of this study is to determine the effect of remote ischemic conditioning on cerebral autoregulation in patients undergoing cerebrovascular stent implantation.
Detailed Description
In this study, 104 cases of patients with cerebrovascular stent implantation will be enrolled in the First Hospital of Jilin University, and they will be divided into the RIC group and the sham-RIC gr...
Eligibility Criteria
Inclusion
- Age≥18 years, regardless of sex;
- Patients with symptomatic or asymptomatic cerebral vascular stenosis (including internal carotid artery system and vertebrobasilar system) who are candidates for elective cerebrovascular stenting.
- Patients or their immediate family members are able and willing to sign informed consent.
Exclusion
- Patients with progressive stroke;
- mRS≥ 2 points before admission;
- Patients with other surgical treatments;
- Patients with other serious diseases or a life expectancy of less than 3 months
- Patients who had contraindication of remote ischemic conditioning, such as severe soft tissue injury, fracture or vascular injury in the upper extremities, venous thrombosis in the acute or subacute stage of upper extremities;
- Laboratory test indicators are unqualified: aspartate aminotransferase or alanine aminotransferase is 3 times higher than the upper limit of the normal range, blood creatinine \> 265umol/L (\>3mg/dl), platelet \< 100×109/L, international normalized ratio (INR), activated partial thromboplastin time (APTT), prothrombin time (PT) exceed the upper limit of the normal range;
- Pregnant or lactating women;
- Patients who are participating in other clinical studies, or who have participated in other clinical studies within 3 months prior to enrollment;
- Unwillingness to be followed up or poor adherence to treatment;
- Other circumstances that the investigator considers unsuitable for enrolment.
Key Trial Info
Start Date :
August 2 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 31 2024
Estimated Enrollment :
104 Patients enrolled
Trial Details
Trial ID
NCT05970653
Start Date
August 2 2023
End Date
August 31 2024
Last Update
February 28 2024
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
First Hospital of Jilin University
Changchun, Jilin, China, 130000