Status:
ACTIVE_NOT_RECRUITING
Physiological MRI for Precision Radiotherapy IDH-wildtype Glioblastoma
Lead Sponsor:
Erasmus Medical Center
Conditions:
Glioblastoma
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
After surgery, a key step in treatment of patients diagnosed with glioblastoma (high grade brain tumour) is radiotherapy. The ideal clinical target volume (CTV) for radiotherapy treatment planning inc...
Detailed Description
Introduction: After surgery, a key step in treatment of patients diagnosed with glioblastoma (high grade brain tumour) is radiotherapy. The ideal clinical target volume (CTV) for radiotherapy treatmen...
Eligibility Criteria
Inclusion
- Informed consent;
- Adults (18 years or older);
- diagnosed with IDH-wildtype glioblastoma, as confirmed by pathology including molecular analysis post resection/biopsy;
- referred to outpatient clinic of the Department of Radiotherapy to undergo standard treatment with high-dose RT.
- Patients eligible for 30x2Gy or 15x2.67Gy
Exclusion
- Contraindication for MRI
- Contraindication for use of gadolinium-based contrast agent (i.e. subject having renal deficiency)
- Unable to give informed consent
Key Trial Info
Start Date :
July 14 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 15 2025
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT05970757
Start Date
July 14 2022
End Date
December 15 2025
Last Update
August 11 2025
Active Locations (1)
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1
Erasmus Medical Center
Rotterdam, South Holland, Netherlands, 3015GD