Status:
COMPLETED
A Study of IBI112 in Chinese Patients With Psoriasis Who Were Previously Treated With Biologics
Lead Sponsor:
Innovent Biologics (Suzhou) Co. Ltd.
Conditions:
Psoriasis
Eligibility:
All Genders
18-75 years
Phase:
PHASE2
Brief Summary
This is a multicenter, open-label study aim to evaluate the efficacy and safety of IBI112 in Chinese participants with plaque psoriasis who were treated with biologics and switched to IBI112. The stud...
Eligibility Criteria
Inclusion
- 18 to 75 years old;
- Evaluated suitable for continuing biologic therapy for plaque psoriasis by the investigator;
- Received previous biologic therapy with at least 4 months.
Exclusion
- Diagnosed with guttate psoriasis, pustular psoriasis, erythrodermic psoriasis, or drug-induced psoriasis (e.g., psoriasis caused by beta blockers, calcium channel inhibitors, etc.) at screening;
- Previously treated with IBI112 or other IL-23 inhibitors;
- Treated with two biologics for psoriasis within 4 months prior to screening;
- Treated with topical therapy for psoriasis within 2 weeks prior to the first dose administration, or treated with systemic non-biological agents or phototherapy within 4 weeks prior to the first dose administration;
- Treated with Natalizumab, or B/T cell regulators (e.g., Rituximab, Abatacept, or Visilizumab) within 12 months prior to the first dose administration;
- Not willing to avoid constant sunshine and other ultraviolet light sources exposure during the study;
- Treated with an investigational biologic within 6 months prior to the first dose administration, or any investigational therapy within 30 days, or an investigational drug within 5 half-lives, or currently participating in a clinical study.
Key Trial Info
Start Date :
August 28 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 26 2025
Estimated Enrollment :
152 Patients enrolled
Trial Details
Trial ID
NCT05970978
Start Date
August 28 2023
End Date
January 26 2025
Last Update
April 27 2025
Active Locations (1)
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1
Dermatology Hospital of Shandong First Medical University (Shandong Provincial Hospitial of Dermatology)
Jinan, Shandong, China, 250000