Status:
COMPLETED
The Effect of Chronic Remote Ischaemic Preconditioning on Blood Pressure in Older Adults
Lead Sponsor:
University of Nottingham
Conditions:
Hypertension
Vascular Diseases
Eligibility:
All Genders
65-85 years
Phase:
NA
Brief Summary
The purpose of this study is to assess whether remote ischaemic conditioning, applied chronically, improves vascular health in older adults
Detailed Description
Hypertension and stroke remain leading causes of mortality across the world (1). Hypertension affects more than 1 in 4 adults and is the 3rd biggest risk factor for premature death and disability in t...
Eligibility Criteria
Inclusion
- Participant is aged \>65y and \<85y.
- Participant is willing and able to give informed consent for participation in the study.
- Participant is physically able to perform RIPC.
Exclusion
- A BMI \<18 or \>35 kg/m2
- Active cardiovascular, cerebrovascular or respiratory disease: e.g. uncontrolled hypertension (BP \> 160/100), active angina, heart failure (class III/IV), arrhythmia, right to left cardiac shunt, recent cardiac event, COPD, pulmonary hypertension or recent (6 mo) stroke.
- If history of hypertension, no recent alteration to antihypertensive medication (3 months).
- A history of, or current neurological or musculoskeletal conditions (e.g. epilepsy)
- Having taken part in a research study in the last 3 months involving invasive procedures or an inconvenience allowance
Key Trial Info
Start Date :
September 25 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2024
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT05971407
Start Date
September 25 2022
End Date
December 31 2024
Last Update
June 4 2025
Active Locations (1)
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1
School of Medicine, Royal Derby Hospital Site, University of Nottingham
Derby, Derbyshire, United Kingdom, DE22 3DT