Status:
RECRUITING
COAgulation Disorders in Ischaemic and Haemorrhagic Stroke
Lead Sponsor:
Ziekenhuis Oost-Limburg
Collaborating Sponsors:
Synapse bv
Conditions:
Ischemic Stroke
Haemorrhagic Stroke
Eligibility:
All Genders
18+ years
Brief Summary
In this study the investigators will assess both procoagulant and anticoagulant pathways using thrombin generation and platelet function tests; as well as neuronal ischemia using cell free DNA in all ...
Detailed Description
In the COADIHS trial the main objective is to map the coagulation profile, both procoagulant and anticoagulant pathways, in patients presenting with acute ischaemic or haemorrhagic stroke. By assessi...
Eligibility Criteria
Inclusion
- Presenting at the hospital with ischaemic stroke, haemorrhagic stroke, aneurysmal subarachnoid haemorrhage or any other type of non-traumatic, intracranial bleeding
- In patients with minor ischemic stroke (NIHSS \<= 4) only baseline lab sampling will be performed (T0 and T0B).
Exclusion
- Refusal of participation by patient or legal representative
- Traumatic intracranial (subdural, subarachnoid, epidural haematoma) bleeding
- Patients receiving treatment with interference on coagulation (pro / anti) before first sampling: in this group of patients the coagulation assessment at presentation will be excluded, further lab sampling is performed according to protocol.
- Patients categorized as having stroke mimic will be excluded from analysis afterwards
Key Trial Info
Start Date :
May 2 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
August 31 2025
Estimated Enrollment :
350 Patients enrolled
Trial Details
Trial ID
NCT05974111
Start Date
May 2 2023
End Date
August 31 2025
Last Update
November 14 2024
Active Locations (1)
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1
Ziekenhuis Oost-Limburg
Genk, Belgium, 3600