Status:

RECRUITING

Prediction of Effectiveness of rTMS Application in Alzheimer's Patients

Lead Sponsor:

Istanbul Medipol University Hospital

Collaborating Sponsors:

Bezmialem Vakif University

Saglik Bilimleri Universitesi

Conditions:

Alzheimer Disease

Eligibility:

All Genders

55+ years

Phase:

NA

Brief Summary

Since pharmacological methods are insufficient in the treatment processes of Alzheimer's disease, non-pharmacological methods such as Transcranial Magnetic Stimulation (TMS) have started to be tried a...

Detailed Description

Since pharmacological methods are insufficient in the treatment processes of Alzheimer's disease, non-pharmacological methods such as Transcranial Magnetic Stimulation (TMS) have started to be tried a...

Eligibility Criteria

Inclusion

  • Have been diagnosed with clinical Alzheimer's Disease in accordance with the NINCDS-ADRDA diagnostic criteria
  • \>55 years old
  • Clinical Dementia Rating Scale (CDR) score in the 1-2 range
  • Not having any other disease that affects their cognitive functions
  • Volunteer to participate in the study

Exclusion

  • Participant or relative does not give consent
  • The patient's inability to participate in the entire study procedure (eg living in another city)
  • The patient's history of head trauma with alcohol/substance abuse
  • Presence of severe stroke and other neurological sequelae disease in the participant
  • Presence of a metal implant on the head or having a pacemaker and contraindications for other TMS applications During the study or 1 month before, having/been receiving/receiving an investigational drug targeting Alzheimer's disease or neuromodulation treatment such as tDCS and TMS, other than standard treatment for AD symptom control such as acetylcholine esterase and memantine, with the potential to affect the study

Key Trial Info

Start Date :

February 16 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 30 2025

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT05977088

Start Date

February 16 2022

End Date

December 30 2025

Last Update

May 2 2025

Active Locations (1)

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1

Medipol University Hospital

Istanbul, Turkey (Türkiye), 34214