Status:

UNKNOWN

PTC Drug Sensitivity Detection to Guide Postoperative Adjuvant of Colorectal Cancer

Lead Sponsor:

Peking Union Medical College Hospital

Conditions:

Colo-rectal Cancer

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

The research objectives is to compare vitro 3D drug sensitivity test results of micro tumor (PTC) with the clinical outcomes of patients, evaluate the consistency between the test results of the techn...

Detailed Description

The study is a multi agency prospective cohort study in China. The subjects were patients aged 18 \~ 75 years with colorectal cancer diagnosed by histopathology or cytology. They must be colorectal ca...

Eligibility Criteria

Inclusion

  • Age 18 \~ 75 years old, regardless of gender
  • Patients with colorectal cancer diagnosed by histopathology or cytology
  • Colorectal cancer patients who need adjuvant therapy after radical surgery and have not received neoadjuvant therapy
  • Having at least one assessable tumor focus
  • ECoG physical condition score ≤ 2 points
  • Voluntarily participate and sign informed consent

Exclusion

  • Patients diagnosed with metastasis
  • Patients who cannot obtain tumor samples
  • Pregnant and lactating women
  • Patients with poor compliance
  • Patients with severe cardiovascular and cerebrovascular complications who cannot receive adjuvant treatment
  • Patients with other malignant tumors
  • Suffering from serious mental and nervous system diseases
  • The researchers believe that patients should not be selected for this study

Key Trial Info

Start Date :

February 14 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 30 2025

Estimated Enrollment :

150 Patients enrolled

Trial Details

Trial ID

NCT05978349

Start Date

February 14 2022

End Date

September 30 2025

Last Update

August 7 2023

Active Locations (1)

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Peking Union Medical College Hospital, Chinese Academy of Medicine Sciences

Beijing, China/Beijing, China, 100000