Status:
RECRUITING
Brain Slice Explants to Predict Drug Response in Brain Tumors
Lead Sponsor:
UNC Lineberger Comprehensive Cancer Center
Conditions:
Central Nervous System Tumor
Eligibility:
All Genders
Brief Summary
This biospecimen collection study will evaluate the feasibility of engrafting and testing resected Central nervous system (CNS) tumors tumor tissue ex vivo to estimate drug response, in pediatric and ...
Eligibility Criteria
Inclusion
- In order to participate in this study a subject must meet all of the eligibility criteria outlined below.
- Written informed consent obtained to participate in the study and HIPAA authorization for the release of personal health information or written assent and parental consent for pediatric subjects or surrogate consent provided by the subject's legally authorized guardians.
- A diagnosis of a tumor residing in the central nervous system with surgery plan to have surgical resection.
- The subject is willing and able to comply with study procedures based on the judgment of the investigator or protocol designer.
Exclusion
- All subjects must not meet any of the following exclusion criteria prior to enrollment to participate in this study:
- Any serious medical or psychiatric disorder that would interfere with the subject's ability to give informed consent.
- Incarcerated individuals.
Key Trial Info
Start Date :
July 27 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 1 2028
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT05978557
Start Date
July 27 2023
End Date
March 1 2028
Last Update
August 29 2025
Active Locations (1)
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1
UNC Lineberger Comprehensive Cancer Center
Chapel Hill, North Carolina, United States, 27516