Status:
COMPLETED
Ticagrelor Versus Clopidogrel for CMD in Patients With AMI: A Retrospective Study Based on the Angio-IMR
Lead Sponsor:
Second Affiliated Hospital, School of Medicine, Zhejiang University
Conditions:
Coronary Heart Disease
Eligibility:
All Genders
18-85 years
Brief Summary
Coronary microvascular dysfunction (CMD) is increasingly recognized as an important indicator for long-term prognosis in patients with acute myocardial infarction (AMI). The angiography-derived index ...
Eligibility Criteria
Inclusion
- Patients who were diagnosed with AMI, including STEMI and NSTEMI, and underwent successful PCI and routine follow-up coronary angiography at the Second Affiliated Hospital of Zhejiang University School of Medicine between June 1, 2017 and May 31, 2020.
Exclusion
- 1\) prior treatment with any P2Y12 inhibitor;
- 2\) need for long-term oral anticoagulation therapy;
- 3\) previous coronary artery bypass grafting (CABG);
- 4\) chronic renal dysfunction with estimated glomerular filtration rate (eGFR) \<30 mL/ (min·1.73 m2) or on hemodialysis;
- 5\) liver cirrhosis ≥Child-Pugh B class;
- 6\) cancer;
- 7\) adjustment of dual antiplatelet therapy (DAPT) during follow-up;
- 8\) inadequate coronary angiographic images.
Key Trial Info
Start Date :
July 1 2017
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 30 2022
Estimated Enrollment :
325 Patients enrolled
Trial Details
Trial ID
NCT05978726
Start Date
July 1 2017
End Date
May 30 2022
Last Update
August 7 2023
Active Locations (1)
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1
Second affiliated Hospital Zhejiang University School of Medicine
Hangzhou, Zhejiang, China, 310009