Status:
ACTIVE_NOT_RECRUITING
Randomized Evaluation of Machine Learning Assisted Radiation Treatment Planning vs Standard Radiation Treatment Planning
Lead Sponsor:
Mayo Clinic
Conditions:
Cancer Head Neck
Cancer, Head
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of this study is to determine the magnitude of clinical benefit achieved through machine learning assisted radiation treatment planning (MLAP) on post-treatment clinical outcomes such as a...
Detailed Description
This is a randomized phase III trial to evaluate the effectiveness of MLAP compared to Standard of Care. Patients will undergo a randomization procedure with a variable allocation ratio where the firs...
Eligibility Criteria
Inclusion
- Age ≥ 18 years at time of registration
- Receiving curative intent intensity modulated radiotherapy for head and neck primary cancer at the discretion of the treating medical doctor (MD)
- Provide written informed consent or allow legally authorized representative to consent on behalf of a participant
- Willing to return to enrolling institution for study follow-up visit
Exclusion
- Incarcerated
- Unable to provide informed consent
- Prior Head and Neck (H\&N) radiation therapy
- Planned radiation dosing LK\<30 Gy or \>76 Gy
Key Trial Info
Start Date :
August 7 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 16 2025
Estimated Enrollment :
204 Patients enrolled
Trial Details
Trial ID
NCT05979883
Start Date
August 7 2023
End Date
December 16 2025
Last Update
August 15 2025
Active Locations (6)
Enter a location and click search to find clinical trials sorted by distance.
1
Mayo Clinic in Arizona
Scottsdale, Arizona, United States, 85259
2
Mayo Clinic in Florida
Jacksonville, Florida, United States, 32224
3
Mayo Clinic Health System in Albert Lea
Albert Lea, Minnesota, United States, 56007
4
Mayo Clinic Health Systems-Mankato
Mankato, Minnesota, United States, 56001