Status:
NOT_YET_RECRUITING
Intravesical Mitomycin C After Diagnostic Ureteroscopy for Upper Tract Urothelial Carcinoma
Lead Sponsor:
McMaster University
Conditions:
Urothelial Carcinoma Ureter
Urothelial Cancer of Renal Pelvis
Eligibility:
All Genders
18+ years
Phase:
PHASE1
Brief Summary
The objective of this pilot study is to determine the feasibility of conducting a phase III randomized trial of intravesical mitomycin C (MMC) for prevention of intravesical recurrence (IVR) after dia...
Eligibility Criteria
Inclusion
- Suspected upper tract urothelial carcinoma (UTUC)
- Diagnostic ureteroscopy required
- Tumor suggestive of upper tract urothelial carcinoma (UTUC) found on ureteroscopy
Exclusion
- Prior or concomitant urothelial carcinoma of the bladder
- History of UTUC
- Ureteroscopy within the preceding six months
- Untreated urinary tract infection
- Suspected or confirmed perforation of the upper or lower urinary tract
- Lower urinary tract fistula
- Leukopenia or thrombocytopenia
- ECOG performance status 2 or greater
- Known hypersensitivity to mitomycin C
- Pregnancy or breastfeeding
- Lack of capacity to consent
Key Trial Info
Start Date :
September 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2027
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT05979909
Start Date
September 1 2023
End Date
September 1 2027
Last Update
August 7 2023
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.