Status:
COMPLETED
Lung Ultrasound Score and Inferior Vena Cava Diameter Compared to Pulse Pressure Variation
Lead Sponsor:
Fayoum University Hospital
Conditions:
Sepsis
Critical Illness
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Evaluation and management of intravascular volume are a central challenge for the critical ill patients. Hypotensive patients are commonly resuscitated with intravenous crystalloid fluid as a recommen...
Detailed Description
The study will be conducted in intensive care units of Fayoum University Hospitals after approval of the local institutional ethics committee and local institutional review board. Hypotensive Patients...
Eligibility Criteria
Inclusion
- Patients on mechanical ventilation (MV).
- Aged more than 18 years.
- Mean arterial pressure (MAP) less than 65 mmHg or systolic arterial pressure less than 90mm Hg with signs of hypoperfusion (urinary flow \< 0.5mL/kg/ h for \> 2hr , tachycardia \> 100 beats/min, or presence of skin mottling , and seurm lactate more than 2 mmol/L).
Exclusion
- Cardiac arrhythmias.
- Previously known significant valvular disease or intracardiac shunt.
- Chest drains.
- Increasing intra abdominal pressure.
- Prephiral vascular disesaes.
- Adult respiratory distress syndrome (ARDS) patients due to low tidal volume.
- Interstitial lung disease because B-lines in these conditions are the consequence of the thickened interlobular septa characterizing fibrosis and are not modified by the state of hydration or imbibition 12
- Any contraindication for fluid administration as cardiogenic shock, acute pulmonary edema or LVEF% less than 50%.
- Renal patients with oliguria and volume overload including patients on hemodialysis or patients with acute anuric renal failure.
- Patients with lower extremity artery/vein thrombosis, significant lower extremity artery plaque, lower extremity artery occlusion, inferior vena cava filter implantation and lower extremity varicose veins.
Key Trial Info
Start Date :
September 13 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 20 2024
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT05980494
Start Date
September 13 2022
End Date
June 20 2024
Last Update
March 12 2025
Active Locations (1)
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1
Fayoum University Hospital
Al Fayyum, Egypt, 63514