Status:
COMPLETED
Neurobiological Similarities of Tinnitus and PTSD
Lead Sponsor:
The University of Texas Health Science Center at San Antonio
Collaborating Sponsors:
Hearing Center of Excellence
National Institute of Mental Health (NIMH)
Conditions:
Posttraumatic Stress Disorder
Tinnitus
Eligibility:
All Genders
18+ years
Brief Summary
Psychiatric distress caused by PTSD may increase attention toward tinnitus, as well as perceived loudness and discomfort. It is important to understand how tinnitus-related distress and PTSD negativel...
Detailed Description
Tinnitus and posttraumatic stress disorder (PTSD) are two of the most common service-connected disabilities for active-duty Service Members and Veterans. Tinnitus and PTSD are highly co-morbid, yet di...
Eligibility Criteria
Inclusion
- Male and female DEERS eligible veterans and active duty service members, ages 18 and above
- preferred language is English and able to read and speak English at a 6th grade level
- those with PTSD (T\&P; PO) must meet full criteria for PTSD diagnosis based on the DSM-5 and assessed by an independent evaluator using the CAPS-5
- those with chronic, constant tinnitus (T\&P, TO) will be identified by self-report and confirmed with the audiometric assessment.
Exclusion
- psychiatric hospitalization in the last 12 months
- significant cognitive impairment determined by inability to comprehend screening assessment
- psychiatric problems and/or high suicide risk warranting immediate intervention
- neurobiological disorders, Meniere's disease
- Temporomandibular disorders that affect tinnitus, per self-report
- history of major head trauma with loss of consciousness for 20 minutes or more as determined by the History of Head Injuries questionnaire
- history of seizures
- conditions that would prevent completion of fMRI scan (any type of electronic, mechanical, or magnetic implant, coil, filter, or stent, any type of surgical clip or staple, shunt, any type of metal object, hearing aid, spinal fusion, halo vest, IV access port, eyelid spring, artificial eye, artificial heart valve, biostimulator, severe hyperacusis)
- active conductive pathology/hearing loss as determined by audiometric assessment.
- Those with tinnitus (T\&P; TO) will be excluded if their tinnitus is intermittent, objective, or pulsatile, or present for less than 6 months.
Key Trial Info
Start Date :
February 4 2021
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
November 1 2024
Estimated Enrollment :
64 Patients enrolled
Trial Details
Trial ID
NCT05981391
Start Date
February 4 2021
End Date
November 1 2024
Last Update
July 8 2025
Active Locations (1)
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1
UT Health San Antonio
San Antonio, Texas, United States, 78229