Status:
COMPLETED
Efficacy Study II on Remote Ischemic Conditioning for the Prevention of Stroke-Associated Pneumonia
Lead Sponsor:
Capital Medical University
Conditions:
Stroke
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Verifying whether remote ischemic adaptation can reduce the occurrence of stroke related pneumonia in acute stroke patients within 24 hours of onset
Detailed Description
Verifying whether remote ischemic adaptation can reduce the occurrence and safety of stroke related pneumonia in acute stroke patients within 24 hours of onset
Eligibility Criteria
Inclusion
- Age≥18 years old;
- Diagnosis of acute ischemic stroke;
- Remote ischemic conditioning or sham-remote ischemic conditioning can be treated within 24 hours after stroke onset
- NIHSS score≥4;
- Subject or his or her legally authorized representative was able to provide informed consent.
Exclusion
- During the screening period, body temperature ≥ 38 ℃;
- Evidence of lung infection, urinary tract infection or other infectious diseases during the screening period
- Expected lifespan less than 7 days
- Mechanical ventilation is expected to be required within 7 days;
- Anti-infective drug were used within 7 days prior to stroke;
- Uncontrolled hypertension with medication (defined as systolic blood pressure ≥200 mmHg and/or diastolic blood pressure ≥110 mmHg);
- There are contraindications for remote ischemic conditioning (such as skin and soft tissue injury, fractures, peripheral arterial disease, etc. in the upper limbs);
- History of autoimmune disease or malignancies;
- Use of immunosuppressive drug within the preceding 3 months;
- Pregnant or lactating, or pregnancy test positive;
- Current participation in another investigational trial;
- Other conditions are not suitable for this trial as evaluated by researchers.
Key Trial Info
Start Date :
January 22 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 19 2024
Estimated Enrollment :
1651 Patients enrolled
Trial Details
Trial ID
NCT05982015
Start Date
January 22 2024
End Date
December 19 2024
Last Update
December 27 2024
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Xuanwu Hospital, Capital Medical University
Beijing, China