Status:

RECRUITING

Impact of Highly Effective Modulator Therapy on the Cystic Fibrosis Microbiome

Lead Sponsor:

Dartmouth-Hitchcock Medical Center

Conditions:

Cystic Fibrosis

Eligibility:

All Genders

18-99 years

Brief Summary

The goal of this observational study is to learn about the effects of a specific cystic fibrosis therapy (Cystic Fibrosis Transmembrane Conductance Regulator Modulator Therapy) on chronic sinonasal di...

Detailed Description

The goal of this study is to characterize the effects of Cystic Fibrosis Transmembrane Conductance Regulator Modulator Therapy on the sinonasal microbial communities and inflammatory profiles in adult...

Eligibility Criteria

Inclusion

  • Subjects between the ages of 18 years old (inclusive) and 99 years old (inclusive)
  • English-speaking
  • Diagnosed with CF as established by genetic testing combined with clinical assessment and/or sweat chloride
  • Patients being seen at the New Hampshire Cystic Fibrosis Center
  • Adults able to sign informed consent

Exclusion

  • Adults unable to consent
  • Individuals who are not yet adults
  • Prisoners

Key Trial Info

Start Date :

November 8 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2026

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT05982795

Start Date

November 8 2023

End Date

December 1 2026

Last Update

December 16 2025

Active Locations (1)

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Dartmouth-Hitchcock Medical Center

Lebanon, New Hampshire, United States, 03756