Status:
RECRUITING
The Immune Landscape of Epithelial Ovarian Cancer
Lead Sponsor:
Oncology Institute of Southern Switzerland
Collaborating Sponsors:
Institute of Oncology Research
Conditions:
Epithelial Ovarian Cancer
Eligibility:
FEMALE
18+ years
Brief Summary
This is a single center prospective observational study to characterize the immune landscape of newly diagnosed epithelial ovarian cancer (OC). Patients with newly diagnosed epithelial OC will be enr...
Eligibility Criteria
Inclusion
- Inclusion criteria cohort A-D:
- Suspicious diagnosis of epithelial ovarian cancer (subsequent histologically confirmation required)
- Plan to undergo a surgical procedure for the management of epithelial ovarian cancer or recurrent ovarian cancer previously treated with conventional treatment and involved in the trial as group A-D
- ≥18 years old
- ECOG Performance Status ≤ 2
- Written informed consent
- Inclusion criteria cohort E:
- Indication for adnexectomy for a benign gynecological condition
- ≥18 years old
- ECOG Performance Status ≤ 2
- Written informed consent
- Exclusion criteria cohort A-E:
- Other active concomitant neoplasms that might confound the results of the planned analysis.
- Ongoing active autoimmune disease requiring treatment or condition of immune deficiency
- Ongoing chronic treatment with steroids or other immune suppressive agents at the time of study entry
Exclusion
Key Trial Info
Start Date :
December 20 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2028
Estimated Enrollment :
74 Patients enrolled
Trial Details
Trial ID
NCT05984875
Start Date
December 20 2022
End Date
December 1 2028
Last Update
November 18 2025
Active Locations (1)
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1
Oncology Institute of Southern Switzerland
Bellinzona, Switzerland, 6500