Status:
RECRUITING
The Daytime Circadian Rhythm in Exhaled Volatile Organic Compounds in People Living Without and Diabetes
Lead Sponsor:
University of Bern
Collaborating Sponsors:
Insel Gruppe AG, University Hospital Bern
DCB Research AG
Conditions:
Diabetes Mellitus
Eligibility:
All Genders
18+ years
Brief Summary
Exhaled volatile organic compounds will be measured during daytime with the goal to identifying circadian variability. The study incudes three subgroups: people without diabetes, people with type 1 di...
Eligibility Criteria
Inclusion
- Inclusion criteria
- Subgroup 1:
- Age 18 or older
- HbA1c below 6.5%
- Written informed consent
- Subgroup 2:
- Age 18 or older
- T1D (Type 1 diabetes) with MDI (multiple daily injection) or CSII (Continuous subcutaneous insulin infusion therapy) therapy \>1 year
- Written informed consent
- Subgroup 3
- Age 18 or older
- T2D (Type 2 diabetes) with oral antidiabetic medication or insulin therapy
- Written informed consent
- Exclusion criteria
- Pregnancy or breastfeeding
- Smoking (last cigarette less than 6 months ago)
- Any chronical lung and intestinal disease diagnosis (such as intestinal bowel disease (IBD); asthma; COPD (chronic obstructive pulmonary disease); lung cancer, …)
- Coeliac disease
- Lactose and fructose intolerance
- Any acute disease diagnosis (such as viral or bacterial infection)
- Drinking habit of more than four units of alcohol per day
- Current inhaled medicines treatments
- Antibiotic treatment in the previous 4 months
Exclusion
Key Trial Info
Start Date :
August 7 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 30 2026
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT05984979
Start Date
August 7 2023
End Date
June 30 2026
Last Update
December 8 2025
Active Locations (1)
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1
University of Bern
Bern, Switzerland, 3010