Status:
RECRUITING
Brain Training to Improve Balance in Parkinson's Disease
Lead Sponsor:
University of Leicester
Collaborating Sponsors:
University of Exeter
University of Nottingham
Conditions:
Parkinson Disease
Eligibility:
All Genders
Phase:
NA
Brief Summary
People living with Parkinson's (PwP) rank balance problems amongst the most disabling symptom. Over time, balance function continues to decline and PwP go on to fall, affecting between 45-68% of PwP. ...
Detailed Description
This is a multi-centre centre study with University of Leicester and DeMontfort University being research sites. NHS organisations will be PIC sites where participants will be identified from. No medi...
Eligibility Criteria
Inclusion
- People with Parkinson with mild-moderate disease and severe disability (but able to stand and walk unaided (Hoehn and Yahr stage ≤4) be eligible if:
- in everyday life, they do less than the recommended aerobic exercise for older adults (i.e., vigorous exercise done \<3 times per week, 20 min per session; or moderate exercise done \<5 times per week, 30 min per session).
- they have experienced at least one fall and one episode of freezing of gait in the past year.
- they are taking stable dopaminergic pharmacotherapy (stable dose for at least 1 month) or are still without treatment and not expected to start treatment within the next 3 months.
- As long as all criteria are met - we will not impose any lower (assuming they are adults) or upper age limit for recruitment.
Exclusion
- severe lower limb motor impairments and/or requirement of a walking aid or wheelchair
- previously diagnosed with stroke or dementia
- having metal implants in the head (i.e. deep brain stimulator or aneurysm clips)
- any other known medical, mental health, or physical condition which may interfere with balance.
- patients on beta-blocking agents or antipsychotics
- patients with other neurological, orthopaedic, or cardiac co-morbidities that make them unfit to do exercise or interferes with balance and cognitive functions required to participate in this study
- patients with psychiatric diseases diagnosed in the past year by a psychiatrist
- patients with dementia
- those unable to tolerate the exergame task.
Key Trial Info
Start Date :
August 4 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2026
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT05986643
Start Date
August 4 2023
End Date
June 1 2026
Last Update
March 27 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Leicester
Leicester, United Kingdom, LE1 7RH