Status:
RECRUITING
BBPA PET/CT in Patients With Malignant Tumors
Lead Sponsor:
Peking Union Medical College Hospital
Collaborating Sponsors:
Peking University
Peking University Cancer Hospital & Institute
Conditions:
Malignant Tumors
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This study is an open-labeled phase II diagnostic clinical trial to explore the safety and clinical value of BBPA-PET/CT in suspected malignant tumor patients. The investigation regarding the clinical...
Detailed Description
In this study, we utilized BBPA, a novel boron amino acid, which replaces the carboxyl group of 4-boronate phenylalanine (BPA) with a boron trifluoride group (-BF3) (-COOH), as a diagnostic molecule f...
Eligibility Criteria
Inclusion
- Have suspected diagnosis of brain tumors, based on clinical performance and imaging results.
- Meet the indications for PET examination, show a clear indication and no contraindications;
- Have a performance status of score ≥80 on KPS scale or score 0-1 points on ECOG scale, a relatively good general situation;
- Does not appear agonal stage, deep coma, over grade 2 major organ dysfunction (heart, lung, liver, kidney and other major organ include), acute or life-threatening status of infection;
- Be ≥ 18 years of age on day of signing informed consent.
- Be willing and able to understand the research content and provide written informed consent/assent for the trial.
Exclusion
- Have a history of imaging agent allergies;
- Does not meet the PET-CT scan sedation requirements, or there are contraindications for PET-CT examination;
- Be pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the trial;
- Unable to adhere strictly to protocol requirements.
Key Trial Info
Start Date :
March 22 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2024
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT05987098
Start Date
March 22 2021
End Date
September 1 2024
Last Update
April 1 2024
Active Locations (1)
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1
Wenbin Ma
Beijing, Beijing Municipality, China, 10005