Status:

RECRUITING

Diagnostic Performance of Small RNA Blood Test in Patients Undergoing Follow-up Imaging After Positive Low Dose CT Screening for Cancer of the Lung

Lead Sponsor:

Hummingbird Diagnostics

Conditions:

Lung Cancer

Eligibility:

All Genders

50-80 years

Brief Summary

2,000 individuals, aged 50-80 who have received a lung-RADS category 3 or 4 result on a LDCT screening study and who are scheduled for follow-up diagnostic imaging study, biopsy, clinical consultation...

Detailed Description

The study is a prospective, longitudinal, observational study to evaluate the performance of a novel diagnostic test for early-stage lung cancer. Study duration: Expected patient enrollment to be com...

Eligibility Criteria

Inclusion

  • Adult male and female patients, aged 50 to 80 years
  • Received a lung RADS category 3 or 4 finding on a LDCT screening exam (first or subsequent) and are referred to undergo further diagnostic procedures for the detection of lung cancer
  • Has undergone LD-CT screening exam within last 90 days and allows for blood sampling within this period
  • Subject may not have undergone any invasive diagnostic procedure in relation to the suspicious nodule
  • Able and willing to provide informed consent

Exclusion

  • Prior history of diagnosed lung cancer
  • History of gastrointestinal, hematological, breast, thyroid, and genitourinary cancer within the past 10 years
  • Active infectious diseases, such blood borne viral diseases (e.g. AIDS, hepatitis)
  • Immunosuppressive medication
  • Deemed not able to participate in the study by the investigator

Key Trial Info

Start Date :

October 18 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2025

Estimated Enrollment :

2000 Patients enrolled

Trial Details

Trial ID

NCT05987189

Start Date

October 18 2023

End Date

December 1 2025

Last Update

January 16 2024

Active Locations (8)

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Page 1 of 2 (8 locations)

1

Northside Hospital

Atlanta, Georgia, United States, 30342

2

Mass General Brigham

Boston, Massachusetts, United States, 02115

3

Henry Ford Health

Detroit, Michigan, United States, 48202

4

Jacobi Medical Center

The Bronx, New York, United States, 10461