Status:
COMPLETED
Effectiveness of Enoxolone on Oral Conditions of Patients With Periodontal Surgery
Lead Sponsor:
Kaohsiung Medical University Chung-Ho Memorial Hospital
Conditions:
Periodontal Surgery
Eligibility:
All Genders
20+ years
Phase:
NA
Brief Summary
Abstract Aim:The Enoxolone (18β-glycyrrhetinic acid; BGA) is a bioactive compound in licorice that exhibits potential anti-ulcer, anti-inflammatory, and anti-microbial activities, relieve oral ulcers,...
Detailed Description
Enoxolone is a toothpaste containing 18β-glycyrrhetinic acid (BGA). In this study, the experimental group used Enoxolone toothpaste, and the control group did not contain BGA toothpaste (Sensodyne), w...
Eligibility Criteria
Inclusion
- Those who are over 20 years old.
- Those whose health or systemic diseases are well controlled.
- Those with severe chronic periodontitis who need to perform periodontal surgery after being diagnosed by a doctor.
- Subjects who are willing to accept this study.
Exclusion
- Allergy to licorice.
- Pregnancy or breastfeeding.
- Periodontal surgery completed at the same site within 6 months.
- Severe bone loss in the apical tissue of the surgical site (including poor prognosis).
- Clinical signs of infection, including fistula, suppuration, fever, severe pain and site swelling.
- Platelets less than 50,000.
Key Trial Info
Start Date :
July 30 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 8 2022
Estimated Enrollment :
27 Patients enrolled
Trial Details
Trial ID
NCT05987722
Start Date
July 30 2021
End Date
December 8 2022
Last Update
August 14 2023
Active Locations (1)
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1
Kaohsiung Medical University Hospital, Kaohsiung Medical University
Kaohsiung City, Taiwan, 807