Status:
COMPLETED
Evaluating Strategies to Improve Guideline Directed Medical Therapy: The GDMT Research, Education & Assist Trial for Heart Failure Care
Lead Sponsor:
Geisinger Clinic
Conditions:
Heart Failure
Heart Failure With Reduced Ejection Fraction
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Heart failure with reduced ejection fraction (HFrEF) is associated with high mortality and adverse events (hospitalization or urgent outpatient visits for HF), along with diminished quality of life. D...
Detailed Description
This is a cluster randomized study designed to evaluate the effectiveness of interventions aimed at improving GDMT in patients with HFrEF. Clinicians stratified based on practice specialty, location, ...
Eligibility Criteria
Inclusion
- Patients aged 18 years or older AND
- Completed visit at included Geisinger cardiology outpatient clinics (office visit or telemedicine) AND
- Clinicians are on a list of currently active Geisinger clinicians in outpatient cardiology clinics who can prescribe heart failure medications AND
- Active problem list diagnosis of HFrEF at time of Cardiology clinic encounter OR Left Ventricular Ejection Fraction (LVEF) \< 40: most recent to the cardiology clinic encounter within 2 years of the visit.
Exclusion
- Currently in hospice or palliative care (ICD 10 code: Z51.5)
- Patient is allergic to each category of GDMT
- Patient is prescribed medications from all four categories of GDMT, including ARNI specifically
Key Trial Info
Start Date :
August 1 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 17 2025
Estimated Enrollment :
4306 Patients enrolled
Trial Details
Trial ID
NCT05990296
Start Date
August 1 2023
End Date
May 17 2025
Last Update
September 19 2025
Active Locations (1)
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1
Geisinger Cardiology Clinics
Danville, Pennsylvania, United States, 17822