Status:

RECRUITING

Estimation of the Diaphragm Electrical Activity and Intercostal Thickening Fraction During Different Pattern of Mechanical Ventilation: PSV Versus NAVA

Lead Sponsor:

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Conditions:

Respiratory Failure

Weaning Failure

Eligibility:

All Genders

18+ years

Brief Summary

the introduction of new MV modalities has shown promising results in reducing the incidence of weaning failure, mainly due to a more physiologic approach which allows respiratory muscle preservation. ...

Detailed Description

Respiratory muscles dysfunction is one of the main causes leading to failure of weaning from mechanical ventilation (MV) in critically ill patients. Muscular activity is important during the inspirato...

Eligibility Criteria

Inclusion

  • patients who have failed at least one weaning attempt
  • mechanical ventilation for at least 24 hours

Exclusion

  • Pregnancy
  • Obesity (Body Mass Index \> 35 kg/m2)
  • Contraindication to the insert of a nasogastric tube
  • Neuromuscular diseases

Key Trial Info

Start Date :

July 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

September 30 2025

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT05990348

Start Date

July 1 2022

End Date

September 30 2025

Last Update

October 18 2024

Active Locations (1)

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Giorgia Spinazzola

Rome, Italy, 00168