Status:
UNKNOWN
French National Cohort MATRIX "Renal and Systemic Thrombotic Microangiopathy"
Lead Sponsor:
University Hospital, Tours
Conditions:
Thrombotic Microangiopathy
Acute Kidney Injury
Eligibility:
All Genders
18+ years
Brief Summary
Thrombotic microangiopathies (TMAs) are a diverse, rare but serious group of diseases. Progress has been made regarding the epidemiology of TMA (Bayer CJASN 2019). It has been shown that secondary TMA...
Detailed Description
Thrombotic microangiopathies (TMAs) are a diverse, rare but serious group of diseases. Their epidemiology has recently been elucidated thanks to work published by our team. It has been shown that seco...
Eligibility Criteria
Inclusion
- Adult patients 18 years of age or older
- Who have undergone renal biopsy of the native kidney for impaired renal function between 2009 and July 2022.
- Presence of classically defined systemic MAT (most of the following parameters: elevated LDH, decreased haptoglobin, schizocytes, thrombocytopenia and anemia) AND/OR presence of arteriolar or glomerular renal MAT as indicated by the pathologist (including endothelial turgor, mesangiolysis, double contours, presence of thrombi, fibrinoid necrosis of the arterial wall).
Exclusion
- 1\. Kidney transplantation
Key Trial Info
Start Date :
January 1 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 1 2025
Estimated Enrollment :
1000 Patients enrolled
Trial Details
Trial ID
NCT05991245
Start Date
January 1 2023
End Date
January 1 2025
Last Update
August 14 2023
Active Locations (1)
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1
Department of Nephrology, University Hospital of Tours
Tours, France, 37044