Status:
UNKNOWN
Dynamic Changes of Serum HBV RNA in Chronic Hepatitis B Patients
Lead Sponsor:
Beijing Friendship Hospital
Conditions:
Chronic Hepatitis B Patients
Eligibility:
All Genders
18+ years
Brief Summary
Some patients with low-level viremia (LLV) are also likely to develop hepatocellular carcinoma (HCC) or other liver diseases. The relationship between HBV RNA levels and fibrosis in patients with HBV ...
Eligibility Criteria
Inclusion
- 18 years old or above and the gender is not limited;
- 2\. Patients who receive antiviral therapy with nucleoside (acid) analogues for 1-3 years ;
- 3\. Patients with HBV DNA negative (HBV DNA\<20 IU/ml) or LLV（HBV DNA 20-2000 IU/mL）
- 4\. Good compliance and voluntary signing of informed consent.
Exclusion
- 1\. Patients with decompensated cirrhosis;
- 2\. Patients co-infection with other viruses, such as hepatitis A virus, hepatitis C virus, hepatitis D virus, hepatitis E virus, HIV virus, etc.;
- 3\. Patients with significant renal, cardiovascular, pulmonary, or neurological disease;
- 4\. Patients have active or suspected malignancy or history of malignancy;
- 5\. Patients who were identified not appropriate for the study by investigators.
Key Trial Info
Start Date :
August 15 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
August 31 2025
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT05991531
Start Date
August 15 2023
End Date
August 31 2025
Last Update
August 16 2023
Active Locations (1)
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1
Beijing Friendship Hospital, Capital Medical University
Beijing, Beijing Municipality, China, 100050