Status:

UNKNOWN

Carotid Plaque Burden in Patients With Philadelphia Negative Myeloproliferative Neoplasms

Lead Sponsor:

Sohag University

Conditions:

Myeloproliferative Neoplasm

Eligibility:

All Genders

18+ years

Brief Summary

In around 90% of the patients with MPNs, an acquired mutation that promotes JAK/STAT signaling is identified \[3, 4\]. The JAK/STAT pathway transduces signals from cytokines including erythropoietin, ...

Detailed Description

All patients will be subjected to a thorough assessment of history, complete clinical examination, and investigations as complete blood picture including neutrophil-lymphocyte ratio which will be anal...

Eligibility Criteria

Inclusion

  • All patients aged 18 years and older who were newly diagnosed to have Philadelphia negative myeloproliferative neoplasms between September 2014 and November 2022 at Sohag university hospital, department of internal medicine, hematology unit and hematology outpatient clinic.

Exclusion

  • Patients were excluded if: (1) their disease of thrombocytosis or polycythemia was determined to be reactive, (2) their disease was not newly diagnosed, (3) their disease met WHO criteria for chronic or acute myeloid leukemia.

Key Trial Info

Start Date :

December 15 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

September 1 2023

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT05993052

Start Date

December 15 2022

End Date

September 1 2023

Last Update

August 15 2023

Active Locations (1)

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1

Faculty of Medicine

Sohag, Egypt