Status:
COMPLETED
Comparative Study Among Different Doses of Ephedrine During Elective Cesarean Section Under Subarachnoid Block.
Lead Sponsor:
Aswan University
Conditions:
Anesthesia
Cesarean Section Complications
Eligibility:
FEMALE
20-40 years
Phase:
PHASE4
Brief Summary
compare the time of second hypotension after administration of three different doses of ephedrine 5,10,15 mg
Detailed Description
In cesarean section, under subarachnoid block the most common complication is hypotension with a reported incidence greater than 80%. Hypotension may occur even after left uterine displacement and pre...
Eligibility Criteria
Inclusion
- American Society of Anesthesiologists 1 and 2 patients
- Gestational amenorrhea of \> 32 weeks
- Elective cesarean section
- Patient willing for spinal anesthesia.
- Singleton pregnancy with cephalic presentation.
- Baseline systolic blood pressure between 100-140 mmHg and diastolic blood pressure between 70-89 mmHg.
Exclusion
- Any contraindication to spinal anesthesia, i.e., local infection at the site of injection
- valvular heat diseases
- bleeding tendency
- any co-morbidity like diabetes mellitus
- liver cirrhosis
- renal failure
- any obstetric complications like placenta previa
- pregnancy-induced hypertension or HELLP syndrome
- multiple gestations
- fetal malformation
- coagulopathies
- morbid obesity and spine deformity
- profound hypotension (total spinal) bradycardia and need atropine and severe bleeding
Key Trial Info
Start Date :
August 20 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2024
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT05993182
Start Date
August 20 2023
End Date
January 1 2024
Last Update
March 1 2024
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Aswan University
Aswān, Egypt, 81511