Status:

COMPLETED

An Evaluation of End-Expiratory Lung Volume and Pulmonary Mechanics With Different PEEP Levels in Mechanical Ventilation in ARDS Patients

Lead Sponsor:

Pamukkale University

Conditions:

Ards

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

ARDS management is quite complex, and mortality is high. PEEP titration is very important in mechanical ventilation. However, the most appropriate approach for PEEP titration has yet to be determined....

Detailed Description

The present study was conducted in the Anesthesiology and Reanimation Intensive Care Units of Pamukkale University Hospital with the approval of Pamukkale University Non-Interventional Clinical Resear...

Eligibility Criteria

Inclusion

  • Patients diagnosed with ARDS according to the Berlin criteria
  • Berlin definition criteria: (1) presence of acute hypoxemic respiratory failure, (2) onset within 7 days of insult, or or new (within 7 days) or worsening respiratory symptoms; (3) bilateral opacities on chest x-ray or CT not fully explained by effusions, lobar or lung collapse, or nodules; and (4) cardiac failure not primary cause of acute respiratory failure.

Exclusion

  • Patients with severe cardiovascular instability (Mean arterial pressure \<60 mmHg , Pulse \<45 or \>150), Patients with pneumothorax, Patients who have undergone pneumonectomy operation, Patients with Lung Transplantation, Patients with thoracic deformity, ARDS patients with cor pulmonale

Key Trial Info

Start Date :

August 2 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 26 2021

Estimated Enrollment :

14 Patients enrolled

Trial Details

Trial ID

NCT05993780

Start Date

August 2 2021

End Date

August 26 2021

Last Update

August 15 2023

Active Locations (1)

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Pamukkale University

Denizli, Turkey (Türkiye)