Status:
COMPLETED
Oxygen Uptake Kinetics During Submaximal Exercise in Adults With Down Syndrome
Lead Sponsor:
University of Nevada, Las Vegas
Conditions:
Down Syndrome
Eligibility:
All Genders
18-35 years
Phase:
NA
Brief Summary
This study aims to compare the rate at which oxygen uptake adapts to submaximal, moderate intensity exercise (oxygen uptake kinetics) between adults with and without Down syndrome, to determine the co...
Detailed Description
Down syndrome (Ds) is the most common chromosomal disorder, affecting approximately 1 in every 800 live births in the US. In addition to a number of comorbidities, individuals with Ds have low cardior...
Eligibility Criteria
Inclusion
- low active (defined as being involved in less than 30 minutes of moderately-intense physical activity per day);
- diagnosis with Down syndrome trisomy 21 (Down syndrome group only);
- normal thyroid function or stable thyroid function (with medications) for at least 6 months (Down syndrome group only).
Exclusion
- asthma or other pulmonary disease;
- severe obesity (defined as BMI \>40);
- uncontrolled hypertension (defined as blood pressure \>130/80 mmHg);
- congenital heart disease;
- diabetes (defined as Hba1c of \>7.5% or use of glucose lowering medication);
- current smoking;
- pregnancy.
Key Trial Info
Start Date :
October 4 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 27 2024
Estimated Enrollment :
28 Patients enrolled
Trial Details
Trial ID
NCT05995223
Start Date
October 4 2023
End Date
June 27 2024
Last Update
July 1 2024
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Nevada, Las Vegas
Las Vegas, Nevada, United States, 89154