Status:

RECRUITING

Immunobiology Blood and Tissue Collection of Upper Aerodigestive Malignancies

Lead Sponsor:

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Collaborating Sponsors:

Stand Up To Cancer

Conditions:

Head and Neck Cancer

Lung Cancer

Eligibility:

All Genders

18+ years

Brief Summary

This research is being done to collect and store biological specimens (biospecimens) from people with cancer, regardless of tumor type, who are receiving treatments known or thought to have an effect ...

Detailed Description

The Immunobiology Blood and Tissue Collection of Upper Aerodigestive Malignancies Protocol is a discovery and exploratory protocol that will enable the investigators to obtain and archive biological s...

Eligibility Criteria

Inclusion

  • Subjects with a pathologically confirmed or clinically suspected upper aerodigestive malignancy who may be candidates for known or potentially immunomodulating treatments
  • Ability to understand and willingness to sign a written informed consent document

Exclusion

  • Patients with known significant contraindications for venipuncture (e.g., hemoglobin \<8.5 g/dL) will be excluded from the blood collection component of the study
  • Patients with known significant contraindications for biopsy (e.g., severe bleeding diathesis) will be excluded from the tissue biopsy component of the study
  • Patients with known significant contraindications for bronchoscopy (e.g., airway concerns, significant cardiac disease) will be excluded from the bronchoscopy component of the study
  • Unable or unwilling to read English and complete forms/questionnaires

Key Trial Info

Start Date :

August 25 2016

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

August 25 2026

Estimated Enrollment :

1250 Patients enrolled

Trial Details

Trial ID

NCT05995821

Start Date

August 25 2016

End Date

August 25 2026

Last Update

November 20 2025

Active Locations (1)

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1

Johns Hopkins University

Baltimore, Maryland, United States, 21287