Status:

RECRUITING

Reinnervated PAP Flap for Oral Cavity and Oropharyngeal Defect Reconstruction

Lead Sponsor:

University Hospital, Basel, Switzerland

Conditions:

Oral Cavity Defect

Oropharynx Defect

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The aim of this study is to investigate sensory recovery and functional outcomes following oral cavity and oropharyngeal defect reconstruction with reinnervated PAP (profunda artery perforator) flaps.

Detailed Description

Tumor resections involving the oral cavity or oropharynx cause significant functional deficits in swallowing and speech and subsequently impair the patients' quality of life. The anterolateral thigh (...

Eligibility Criteria

Inclusion

  • \- Patient with defect involving the oral cavity or oropharynx who undergo reconstruction with a free reinnervated profunda artery perforator flap

Exclusion

  • \<18 years old
  • Defect localizations other than the oral cavity or oropharynx
  • Not able to give informed consent
  • Inability to follow the procedures of the study, e.g., due to psychological disorders, dementia
  • Inability or contraindications to undergo the investigated intervention

Key Trial Info

Start Date :

September 1 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 1 2027

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT05997186

Start Date

September 1 2023

End Date

May 1 2027

Last Update

February 18 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

University Hospital Basel

Basel, Switzerland, 4031