Status:
RECRUITING
Effect of Repetitive TMS on Executive Function in Alcohol Use Disorder
Lead Sponsor:
Universidad Nacional Autonoma de Mexico
Collaborating Sponsors:
National Council of Science and Technology, Mexico
Conditions:
Alcohol Use Disorder
Eligibility:
All Genders
25-59 years
Phase:
NA
Brief Summary
Alcohol Use Disorder (AUD) is a major public health problem that affects the physical, social, family, and mental integrity of the sufferer. Behavioral self-regulation is compromised in AUD, and a ben...
Detailed Description
It is proposed that individuals predisposed to developing alcohol use disorder (AUD) exhibit alterations in executive functions, resulting from maladaptive cellular homeostatic processes and neuronal ...
Eligibility Criteria
Inclusion
- Men and women of 25 to 59 years old
- The reading level of at least 6th grade of primary (equivalent to fifth grade of elementary school).
- Alcohol users with and AUDIT ≥ 20 puntos
- Abstinence from alcohol consumption from 8 weeks to 5 years, with CIWA-Ar scale scores ≤ 9 points.
- No disabling neuropsychiatric conditions (i.e. Schizophrenia)
- No substance use disorders except alcohol and nicotine.
- BrAC (Breath Alcohol) = 0.00 mg/dl in each of the assessments.
- No traces of alcohol consumption using urine test strips.
- No contraindications for TMS therapy.
Exclusion
- Individuals with symptoms of severe agitation or who are unable to cooperate in the study
- History of epilepsy
- Sudden onset of stroke, focal neurological findings such as hemiparesis, sensory loss, visual field deficits and lack of coordination.
- Seizures or gait disturbances
- History of severe psychiatric disorders.
- Alterations in a conventional electroencephalogram.
- Pacemakers or intracranial metallic objects.
- Elimination criteria
- At the subject's request
- The presence of adverse incidents that deteriorate the subject's health and would limit continuation of rTMS treatment.
- Exacerbation of cognitive or behavioral symptoms during treatment.
Key Trial Info
Start Date :
March 16 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 1 2026
Estimated Enrollment :
44 Patients enrolled
Trial Details
Trial ID
NCT05997212
Start Date
March 16 2024
End Date
November 1 2026
Last Update
February 10 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Unidad de Resonancia Magnética
Querétaro City, Querétaro, Mexico, 76230