Status:

COMPLETED

Evaluation of the Effect of Triamcinolone at Different Doses on LIA During TKA

Lead Sponsor:

Peking University Third Hospital

Conditions:

Osteoarthritis, Knee

Eligibility:

All Genders

50-85 years

Phase:

PHASE4

Brief Summary

To evaluate the efficacy and safety of different doses of triamcinolone for local infiltration analgesia during total knee replacement

Detailed Description

Participants were enrolled according to protocol requirements. Patients who meet all inclusion criteria and do not have any exclusion criteria will be considered for inclusion in the study and will pr...

Eligibility Criteria

Inclusion

  • age in the range of 50 to 85 years old
  • patients with knee osteoarthritis requiring primary unilateral total knee replacement
  • the body mass index in the range of 18 to 36 kg/m2
  • possess the physical status I-III of American Society of Anesthesiologists
  • the patient and his family members agree and sign the informed consent

Exclusion

  • Non-osteoarthritis (rheumatoid arthritis, traumatic arthritis, septicemic arthritis, etc.)
  • History of knee surgery or knee injury, such as high tibial osteotomy, meniscus repair, ligament reconstruction, etc
  • Flexion deformity ≥30°, internal and external varus deformity ≥15°
  • People allergic to the drugs used in this study
  • Patients who had used glucocorticoids within 3 months before surgery

Key Trial Info

Start Date :

April 25 2023

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2024

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT05997238

Start Date

April 25 2023

End Date

May 1 2024

Last Update

June 13 2024

Active Locations (1)

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Peking University Third Hospital

Beijing, Beijing Municipality, China, 100181