Status:

COMPLETED

Continuous Norepinephrine Administration and Blood Pressure Stability During Anesthetic Induction

Lead Sponsor:

Universitätsklinikum Hamburg-Eppendorf

Conditions:

Blood Pressure

Perioperative Hypotension

Eligibility:

All Genders

45+ years

Phase:

NA

Brief Summary

This is a randomized trial investigating whether continuous norepinephrine administration via an infusion pump - compared to manual bolus administration - increases blood pressure stability within the...

Detailed Description

not provided

Eligibility Criteria

Inclusion

  • age ≥ 45 years
  • American Society of Anesthesiologists physical status II-IV
  • scheduled for elective major non-cardiac surgery under general anesthesia
  • continuous intraarterial blood pressure monitoring using a radial arterial catheter for clinical indications not related to the trial
  • sinus rhythm

Exclusion

  • Clinical indication to use a continuous norepinephrine infusion via an infusion pump during anesthetic induction
  • Need for femoral artery catheterization
  • History of intracranial bleedings or aneurysms
  • Patients who are incapable of giving consent
  • Pregnancy

Key Trial Info

Start Date :

September 8 2023

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 19 2024

Estimated Enrollment :

72 Patients enrolled

Trial Details

Trial ID

NCT05997303

Start Date

September 8 2023

End Date

April 19 2024

Last Update

May 17 2024

Active Locations (1)

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Universitätsklinikum Hamburg-Eppendorf

Hamburg, Germany, 20251

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